Sodium methoxide vs potassium tert-butoxide. Sodium tert-butoxide is the chemical compound with the formula (CH3)3CONa. Sodium tert-butoxide is a strong base and a non-nucleophilic base. Sodium tert-butoxide can be produced by treating tert-butyl alcohol with sodium hydride. Sodium tert-butoxide CAS Number: 865-48-5. Sodium Tert-butoxide Chemical Information Density 1,104 g/cm3 Boiling Point 180°C/1mmHg Melting Point 180 °C Molecular Formula C4H9NaO Molecular Weight 96.103 Flash Point 12°C Storage condition Flammables area Water Solubility reacts Sodium Tert-butoxide Structure Sodium Tert-butoxide Application 1. Used as an intermediate for organic synthesis and pharmaceutical intermediates 2. As a strong base, it is widely used in the condensation, rearrangement and ring opening reactions in organic synthesis such as chemical, pharmaceutical and pesticide.